As far as what has been removed from the website, perhaps most notable are the black and silver Aquaracer quartz chronographs. I can't say I'm that surprised as they never seemed likely to be that popular. You can still get them in the blue and lilac/blue dial variants though. Also the black DLC Autavia flyback seems to have gone, the base 43mm Aquaracers (to make way for the new 42mm models obviously) and also the not that old really white/blue bezel GMT Aquaracers. Again, not sure anyone will miss those...
The yellow highlighted CBN2A1H Porsche Racing Carrera has gone too, as have both the 42mm Year of the Dragon Carreras and the previous 44mm Year of the Rabbit Carrera. Obviously the 2023 Indy 500 has made way for the new version and the Super Mario Formula 1 Tourbillon has also disappeared. Finally, not surprisingly, the limited edition CBL2181 'Night Driver' Monaco has gone too...